Growth factor eye serums, like the ZO Growth Factor Eye Serum, work by utilizing growth factors, which are naturally occurring proteins that stimulate skin repair and regeneration. These proteins signal skin cells to produce collagen, leading to improved skin density, firmness, and a reduction in the appearance of fine lines and wrinkles. Additionally, some serums contain other ingredients like neuropeptides and enzymatic vasodilators that address specific concerns like puffiness and dark circles.